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In studies with sound volunteers of single doses up to 800 mg, inauspicious reactions were standardised to those seen at bring down doses only incidence rates and severities were increased. Physicians should monish patientsthat drawn-out erections greater than 4 hours and priapism (unspeakable erectionsgreater than 6 hours in duration) consume been reported infrequently since marketapproval of Viagra. In the case of an hard-on that persists longer than 4hours, the patient should assay immediate checkup assist. If priapism is nottreated immediately, penial tissue legal injury and permanent expiration of potency mayresult [see WARNINGS AND PRECAUTIONS]. Physicians should advisepatients of the possible for Sildenafil citrate to augment the lineage pressure loweringeffect of alpha-blockers and anti-hypertensive medications. Concomitantadministration of Sildenafil citrate and an alpha-blocker Crataegus laevigata head to symptomatichypotension in around patients.
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