However, in vitro studies withhuman platelets indicate that sildenafil potentiates the antiaggregatory effectof sodium nitroprusside (a nitric oxide donor). In addition, the combination of heparin and VIAGRA had an additive effect on bleeding time in the anesthetizedrabbit, but this interaction has not been studied in humans. VIAGRA has systemic vasodilatory properties and mayfurther lower blood pressure in patients taking antihypertensive medications. Co-administration of ritonavir, a strong CYP3A4 inhibitor, greatly increased the systemic exposure of sildenafil (11-fold increase in AUC). It is therefore recommended not to exceed a maximum single dose of 25 mg of VIAGRA in a 48 hour period [see DOSAGE AND ADMINISTRATION, WARNINGS AND PRECAUTIONS, CLINICAL PHARMACOLOGY].
Before you start Viagra or any other medications, tell your doctor buy xanax without prescrition about any other drugs you take. Your doctor can tell you if there are any interactions that may happen. But a rare side effect of Viagra is swelling of your genitals, including your penis. This may make your penis look bigger, even when you’re not sexually stimulated. Tell your doctor if you have swelling of your penis with Viagra.
Serious side effects
You may need to have your blood pressure monitored while you take this drug. Medicines that you take by mouth are called oral medicines. They're often the first line of treatment for trouble getting or keeping an erection, called erectile dysfunction (ED). Oral medicines for ED usually work well and cause few side effects.
Risks of Online ED Drugs
They’ll be able to determine how low your blood pressure is and whether it’s at a safe level. Mild side effects of many drugs may go away within a few days or a couple of weeks. But if they become bothersome, talk with your doctor or pharmacist. Like most drugs, Viagra may cause mild or serious side effects. The lists below describe some of the more common side effects that Viagra may cause.
It’s possible that drinking alcohol while you’re taking Viagra may cause low blood pressure. Both Viagra and alcohol can cause your blood pressure to decrease. So this combination may cause your blood pressure to drop too low, which can be unsafe. Taking medications, vaccines, foods, and other things with a certain drug can affect how the drug works.
Also collected as part of the IIEF was information about other aspects of sexual function, including information on erectile function, orgasm, desire, satisfaction with intercourse, and overall sexual satisfaction. Sexual function data were also recorded by patients in a daily diary. In addition, patients were asked a global efficacy question and an optional partner questionnaire was administered. Most of the therapeutic trials done and published by doctors who have been paid or honorary consultants to the drug manufacturing companies. More data that is objective is likely to emerge once the drug is tested on a much larger scale by more doctors. Lot of concern has been generated by reported death of patients after taking sildenafil and engaged in sexual activity.